【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
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答案
A
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相关试题
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
A. 对
B. 错
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
A. 对
B. 错
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
A. 对
B. 错
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
A. 对
B. 错
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
A. 对
B. 错
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
A. 对
B. 错
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
A. 对
B. 错
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
A. 对
B. 错
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
A. 对
B. 错
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
A. 对
B. 错
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
A. 对
B. 错
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
A. 对
B. 错
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
A. 对
B. 错
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
A. 对
B. 错
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
A. 对
B. 错
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
A. 对
B. 错
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
A. 对
B. 错
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
A. 对
B. 错
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
A. 对
B. 错
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
A. 对
B. 错
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
A. 对
B. 错
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
A. 对
B. 错
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
A. 对
B. 错
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
A. 对
B. 错
【单选题】
（3）生物圈的范围为___
A. 大气圈、水圈和岩石圈的全部
B. 大气圈和水圈的全部、岩石圈的上部
C. 大气圈的底部、水圈和岩石圈的全部
D. 大气圈的底部、水圈的全部和岩石圈的上部
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C. 精心安排，制定策略
D. 执行计划，付诸实践
【单选题】
检验认识的真理性，就是要检验人们的认识是否___
A. 与多数人的愿望和要求相符合
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有人认为只有写到书本上的理论才是真实可靠的，从而不顾实际情况，死搬书本上的教条。这在认识论上犯了类似于___
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一个正确的认识需要多次反复才能完成，并且认识是永无止境的发展过程。这说明人类的认识是___
A. 感性和理性的统一
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C. 正确和错误的统一
D. 有限和无限的统一
【单选题】
实践之所以成为检验真理的唯一标准是由___
A. 真理的主观性和实践的客观性所要求的
B. 真理的相对性和实践的决定性所预设的
C. 真理的属性和实践的功能所规定的
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爱迪生在发明电灯之前做了两千多实验，有个年轻的记者曾经问他为什么遭遇这么多次失败。爱迪生回答：“我一次都没有失败。我发明了电灯。这只是一段经历了两千步的历程。”爱迪生之所以说“我一次都没有失败”，是因为他把每一次实验都看作___
A. 认识中所获得的相对真理
B. 整个实践过程中的一部分
C. 对事物规律的正确反映
D. 实践中可以忽略不计的偶然挫折
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C. 理论对实践的指导作用没有正确与错误之分
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【单选题】
霍金以其“黑洞理论”闻名于世，但他并未因此获诺贝尔奖。有诺贝尔委员会委员认为，原因在于霍金这一理论还没有得到验证；霍金也承认是因为他的黑洞蒸发还没有被观测或者被实验所证实。这说明___
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B. 实践是认识的目的
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D. 世界是可以被认识的
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D. 掌握和运用系统优化的方法，才能促成认识的发展
【单选题】
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A. 物质资料的生产方式是人类社会存在和发展的基础
B. 生产力决定生产关系，生产关系一定要适合生产力状况
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D. 上层建筑一定要适应经济基础
【单选题】
社会历史观的基本问题是___
A. 生产力和生产关系的问题
B. 社会规律的客观性和主观能动性的关系问题
C. 社会存在和社会意识的关系问题
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马克思把人类社会历史划分为依次更替的五种社会形态：原始社会、奴隶社会、封建社会、资本主义社会、共产主义社会（社会主义社会是它的第一阶段）。五种社会形态划分的依据是___
A. 人的发展状况
B. 自然地理环境的状况
C. 生产力的水平
D. 生产关系的性质
【单选题】
人类社会发展的一般规律是___
A. 生产方式内部的矛盾规律
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我国农村推广多种形式的承包责任制之所以促进了生产力发展，在于它遵循了___
A. 生产关系适合生产力发展状况的规律
B. 上层建筑适合经济基础的规律
C. 社会存在决定社会意识的规律
D. 阶级斗争推动阶级社会发展的规律
