【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
查看试卷，进入试卷练习
微信扫一扫，开始刷题
答案
D
解析
暂无解析
相关试题
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
A. 对
B. 错
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
A. 对
B. 错
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
A. 对
B. 错
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
A. 对
B. 错
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
A. 对
B. 错
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
A. 对
B. 错
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
A. 对
B. 错
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
A. 对
B. 错
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
A. 对
B. 错
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
A. 对
B. 错
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
A. 对
B. 错
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
A. 对
B. 错
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
A. 对
B. 错
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
A. 对
B. 错
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
A. 对
B. 错
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
A. 对
B. 错
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
A. 对
B. 错
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
A. 对
B. 错
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
A. 对
B. 错
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
A. 对
B. 错
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
A. 对
B. 错
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
A. 对
B. 错
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
A. 对
B. 错
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
A. 对
B. 错
【单选题】
（3）生物圈的范围为___
A. 大气圈、水圈和岩石圈的全部
B. 大气圈和水圈的全部、岩石圈的上部
C. 大气圈的底部、水圈和岩石圈的全部
D. 大气圈的底部、水圈的全部和岩石圈的上部
【单选题】
（8）地球的表面积约为5.1亿平方千米，表面起伏不平，凸出来的地方成为陆地和山脉，而大片大片下凹的部分经过亿万年的积累，被液态海水所淹没而变成了海洋，海洋面积占地球表面积的近___。
A. 2％
B. 51%
C. 71%
D. 91%
推荐试题
【单选题】
启动离心泵的步骤正确的是（ ）。___
A. 盘泵查看转动情况，试启动电动机观察运转方向，再向泵和吸水管内灌满水，打开排水阀门，最后启动离心泵
B. 盘泵查看转动情况，再向泵和吸水管内灌满水，打开排水阀门，最后启动离心泵
C. 盘泵查看转动情况，试启动电动机观察运转方向，打开排水阀门，最后启动离心泵
D. 试启动电动机观察运转方向，再向泵和吸水管内灌满水，打开排水阀门，最后启动离心泵
【单选题】
气动绞车主要由（ ）组成。___
A. 动力部分.传动部分.卷扬部分
B. 气缸. 连杆.配气阀.操纵手柄及进气口等
C. 转动轴.曲轴.离合器.大小齿轮
D. 卷筒及其制动装置
【单选题】
气动绞车刹带及刹车鼓之间要保持清洁干燥，防止油.污水进入，刹车效果不好可通过调节（ ）进行，严禁往刹带内塞面纱等物。___
A. 刹车手柄螺栓
B. 活塞销
C. 离合器手柄
D. 曲轴
【单选题】
以下关于气动绞车使用，不正确的是：（ ）。___
A. 在刹死刹车后，人可以在吊重物期间离开
B. 不要用手去排绳子
C. 眼睛要观察指挥手势.吊物及绳子排放情况
D. 刹带及刹车鼓之间要保持清洁干燥，防止油污水等进入
【单选题】
关于吊带下列描述不正确的是（ ）。___
A. 使用时应避免软环张开角度超过30°
B. 吊带应在避光和无紫外线辐射的条件下存放
C. 不应把吊装带存放在明火旁或其他热源附近
D. 不使用吊装带时，应将吊带放置在光线好的地方上
【单选题】
如果钻井绞车刹车过热，则下面做法不正确的是（ ）。___
A. 提高进水排量到推荐值
B. 增加水箱的冷却水或增大水箱容积
C. 关闭报警装置
D. 当转子旋转时，减缓冷却水流畅速度
