【单选题】
14. We will have a _________ holiday after the exam. A. two-month B. two month’s C. two month D. two-months
A. A
B. B
C. C
D. D
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答案
A
解析
A
相关试题
【单选题】
15. —We will build an underground in Xuzhou before 2015. — Wow, _______! Will it pass our place? A. what an excited news B. how excited the news is C. what exciting news D. how exciting
A. A
B. B
C. C
D. D
【单选题】
16. — Emily, here’s a dictionary.I hope it will help you in some way. — Thank you.It’s ________ what I need. A. almost B. still C. only D. just
A. A
B. B
C. C
D. D
【单选题】
17. —Oh.I’m hungry.Mum, can I have the hamburger on the plate? —No.It tastes . A. terribly B. terrible C. good D. well
A. A
B. B
C. C
D. D
【单选题】
18. —We can invite our teachers to the farewell party next Saturday. —Yes, ______? I’ll call them at once. A. what for B. what C. why not D. why
A. A
B. B
C. C
D. D
【单选题】
19.You can ________ ask the old man to move away to any other place because he has lived ________ here for at least sixty years. A. hardly; alone B. hard; alone C. hardly; lonely D. hardly; lonely
A. A
B. B
C. C
D. D
【单选题】
20.—I’m going back to see my grandparents this weekend. —________. A. It’s very nice of you B. You’d better hurry C. Say goodbye to them D. Give my best wishes to them
A. A
B. B
C. C
D. D
【单选题】
21.—Why not take ____ umbrella with the sign “Made in China”? It is useful. —What _______ good advice it is!    A. an; a B. a; a C. an; \ D. \; a
A. A
B. B
C. C
D. D
【单选题】
22. —Do you know the boy________ is sitting next to Peter? — Yes. He is Peter’s friend. They are celebrating his ________ birthday. A. who; ninth B. that; ninth C. /; ninth D. which; ninth
A. A
B. B
C. C
D. D
【单选题】
23. It was dark, ______ I couldnt see what was happening. A. or B. though C. but D. so
A. A
B. B
C. C
D. D
【单选题】
24.—You can use MSN to talk with Vivien on the Internet. —I know. But can you tell me ________? A. what I can use it B. when I can use it C. why can I use it D. how can I use it
A. A
B. B
C. C
D. D
【单选题】
25. _______ are you going to the School Uniform Exhibition, Amy ? To learn about different styles of school uniform. A. What B. Where C. Which D. Why
A. A
B. B
C. C
D. D
【单选题】
( ) 26. Where does the writer of "The little Prince" come from? A.England. B.France. C.America. D.China.
A. A
B. B
C. C
D. D
【单选题】
( ) 27. What does the prince do after the fox tells him a secret? A.He cares more about a flower and a sheep. B.He meets many more strange adults on other planets. C.He realizes his love for the rose and he goes back to his planet.   D.He discovers interesting things such as a snake, other roses and a fox
A. A
B. B
C. C
D. D
【单选题】
( ) 28. What does "The little Prince" mainly talk about? It' s about _________. A.the adult world B.the planet B -612 C.a rose and a fox D.the adventure of a young prince
A. A
B. B
C. C
D. D
【单选题】
( ) 29. What is the writer's main purpose(目的)in writing this passage?    A.To tell the readers his life story.    B.To tell people what kind of person his father was.    C.To tell the readers what present he got from his father.    D. To let people know how poor he was.
A. A
B. B
C. C
D. D
【单选题】
( ) 30. Why did the father not ask his son not to do this and do that?    A.Because he felt quite confident of his son.    B.Because he was born from a poor family.    C.Because he was a man of few words.    D.Because he didn't want to be much too strict with his son.
A. A
B. B
C. C
D. D
【单选题】
( ) 31. What would someone learn from this passage?    A.How to live by oneself. B.How to stand on one's own feet.    C.What a good father should do. D.What the self-important is like.
A. A
B. B
C. C
D. D
【单选题】
( ) 32. What may be the proper Chinese for the underlined part in the passage?    A.闲暇时光 B.学费 C.精神空虚 D.经济不足
A. A
B. B
C. C
D. D
【单选题】
( ) 33. Why did Natalie Smith pay for the six cars behind her? A. She had seven tickets. B. She hoped to please others. C. She knew the car drivers well. D. She wanted to show kindness.
A. A
B. B
C. C
D. D
【单选题】
( ) 34. Judy Foreman copied down the phrase because she ___ . A. thought it was beautifully written B. wanted to know what it really meant C. decided to write it on a warehouse wall D. wanted her husband to put it up in the classroom
A. A
B. B
C. C
D. D
【单选题】
( ) 35. Who came up with the phrase according to the passage? A. Judy Foreman. B. Natalie Smith. C. Anne Herbert D. Alice Johnson.
A. A
B. B
C. C
D. S
【单选题】
( ) 36. What can we infer from the last paragraph? A. People should practice random kindness to those in need. B. People who receive kindness are likely to offer it to others. C. People should practice random kindness to strangers they meet. D. People who receive kindness are likely to pay it back to the giver.
A. A
B. B
C. C
D. D
【单选题】
( ) 37.The greatest river for navigation is ___________. A. the Nile B. the Amazon C. the Mekong D. the Mississippi
A. A
B. B
C. C
D. D
【单选题】
( ) 38. From a dam, people can use the water for ___________. A. keeping the rivers clean B. only making electricity C. irrigation and making electricity D. washing clothes
A. A
B. B
C. C
D. D
【单选题】
( ) 39. The water in the river is polluted because of _____________. A. people's drinking water too much B. people's swimming in the river too much C. chemicals and other materials D. people's building a dam across a river
A. A
B. B
C. C
D. D
【单选题】
( ) 40. The best title of the passage is ___________. A. Rivers in Cities B. The importance of Rivers C. Transportation D. Natural Resources
A. A
B. B
C. C
D. D
【单选题】
) 1. Even Tony’s six-year-old son asked him ______ smoking. A. stops B. stopped C. to stop D. stopping
A. A
B. B
C. C
D. D
【单选题】
2.—What do you think of the lecture of Li Yang’s Crazy English? — I think it’s _______ , but someone thinks it’s much too ________. A. wonderful enough; bored B. enough wonderful; boring C. enough wonderful; bored D. wonderful enough; boring
A. A
B. B
C. C
D. D
【单选题】
3.—He didn’t go to the lecture this morning, did he?    — _____ .Though he was not feeling very well. A. No, he didnt B. Yes; he did C. No, he did D. Yes, he didnt
A. A
B. B
C. C
D. D
【单选题】
4. If you read a lot, your life ______ full of pleasure. A. will be B. is C. be D. was
A. A
B. B
C. C
D. D
【单选题】
5. The black bag _________ be Annas. She has a blue one. A. should B. cant C. wouldnt D. could
A. A
B. B
C. C
D. D
【单选题】
6. Susan, why are you still here? They are all ready to start. Im sorry, but I _________ when to start. A. dont tell B. wasnt told C. didnt tell D. havent told
A. A
B. B
C. C
D. D
【单选题】
7.—Why dont you choose the red tie?    —For me, it doesn’t _____ my shirt very well. A. fix B. accept C. compare D. match
A. A
B. B
C. C
D. D
【单选题】
8. — Could you tell me ______? I must find him. — Sorry.I don’t know.But he was here just now. A. where Tom was B. where Tom is C. where has Tom gone D. where can I find Tom
A. A
B. B
C. C
D. D
【单选题】
9. —What did Mr Green say to you? — What a heavy rain! How did you come here? He asked________. A. at all B. in fact C. in surprise D. as a result
A. A
B. B
C. C
D. D
【单选题】
10. I often see Tom on the playground.When I passed the playground yesterday, I saw him . A. play; playing B. to play; play C. playing; to play D. playing; play
A. A
B. B
C. C
D. D
【单选题】
11. — Mum, could I have ____________ to drink? — Oh, dear.You can only drink some water.There is _________ in the kitchen. A. anything; else something B. anything; something else C. something; else nothing D. something; nothing else
A. A
B. B
C. C
D. D
【单选题】
12. We all know that learning a foreign language _______ time and effort. A. requires B. reduces C. removes D. repeats
A. A
B. B
C. C
D. D
【单选题】
13. Her son __________ Coke, but now he __________ milk. A. is used to drinking; used to drink B. used to drink; uses to drink C. used to drink; is used to drinking D. is used to drink; is drinking
A. A
B. B
C. C
D. D
【单选题】
14. I don’t know the teacher is talking with Miss Wang. A. what B. whom C. who D. which
A. A
B. B
C. C
D. D
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【多选题】
与伊马替尼相比格列卫,达希纳作为一线治疗的优势是()。
A. Earlier,更早的分子学反应
B. Deeper,更深的分子学反应
C. Fewer,更少的疾病进展风险
D. 所有选项均不正确
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在达希纳给药前必须纠正(),在治疗期间必须其血药浓度进行定期检测。
A. 有临床表现的脱水并治疗高尿酸血症
B. 低钾血症
C. 低镁血症
D. 高钾血症
【多选题】
早期的分子学反应(3个月时Bcr-Abl水平)与以下哪个长期预后相关?
A. 疾病进展风险
B. 总生存率
C. MR4.5
D. 所有选项均不正确
【多选题】
中国CML指南推荐,对妊娠期间确诊的女性CML—CP患者,因有时白细胞分离术不能满意地控制血小板计数,故可予以()抗凝。
A. 阿司匹林
B. 低分子肝素
C. 维生素K3
D. 以上所有选项均错误
【多选题】
2013 ELN 推荐切换至二代TKI3个月时BCR-ABLIS ≤ 1% 被认为达到最佳反应。
A. 是
B. 否
C.
D.
【多选题】
2013版中国CML指南推荐:移植后3月起TKI治疗1年,预防复发。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗失败的标准为,任何时间丧失CHR或CCyR或MMR,出现伊马替尼或其他TKI耐药性突变,出现Ph染色体基础上其他克隆性染色体异常。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗失败的标准为12个月未达到CCyR。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗失败的标准为18个月未达到CCyR。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗失败的标准为3个月无任何CyR。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗失败的标准为6个月未达到CCyR。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗最佳反应的标准为12个月达到CCyR或BCR-ABL(IS)≤1%。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗最佳反应的标准为12个月获得MMR。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南定义一线格列卫治疗最佳反应的标准为6个月至少达到PCyR或BCR-ABL(IS)≤10%。
A. 是
B. 否
C.
D.
【多选题】
2016中国CML指南推荐,每3个月进行1次分子学检测,直至获得稳定MMR即可停止监测
A. 是
B. 否
C.
D.
【多选题】
CML-CP患者获得部分细胞遗传学反应的定义为Ph+ 1%-35%。
A. 是
B. 否
C.
D.
【多选题】
CML-CP患者获得完全分子学反应的定义为定量PCR检测不到BCR-ABL转录本,巢式PCR检测阴性。
A. 是
B. 否
C.
D.
【多选题】
CML-CP患者未获得细胞遗传学反应的定义为Ph+ >95% 。
A. 是
B. 否
C.
D.
【多选题】
CML-IV研究中位随访3年时,无患者出现证实的MR4.5进展
A. 是
B. 否
C.
D.
【多选题】
CML常规染色体分析,检测20-30个有丝分裂中期的骨髓细胞中有多少Ph+细胞。
A. 是
B. 否
C.
D.
【多选题】
CML患者FISH检测的样本来源于外周血/骨髓,检测敏感度为0.5-5%,可用于CML诊断、常规细胞遗传学疗效和微小残留病变检测。
A. 是
B. 否
C.
D.
【多选题】
CML患者RT-PCR检测的样本来源于外周血/骨髓,检测敏感度可达0.0001-0.001%,可用于常规微小残留病变和融合基因断裂点检测。
A. 是
B. 否
C.
D.
【多选题】
CML患者分子学水平检测的疗效结果为MMR和CMR等。
A. 是
B. 否
C.
D.
【多选题】
CML患者染色体核型分析样本来源于外周血,检测敏感度仅有1-5%,可用于CML诊断和分析费城染色体之外的染色体异常。
A. 是
B. 否
C.
D.
【多选题】
CML患者细胞遗传学水平检测的疗效结果描述为MMR和CMR等。
A. 是
B. 否
C.
D.
【多选题】
CML治愈之路是诺华和CML社区的一项长期合作,包括对CML更好的理解,改进检测和监测手段和优化治疗方案,从而使患者实现更好的转归。
A. 是
B. 否
C.
D.
【多选题】
CMR是指完全分子学反应。
A. 是
B. 否
C.
D.
【多选题】
ENESTcmr研究中伊马替尼进行一线治疗的CML患者,较继续使用伊马替尼,更多的患者通过二线达希纳获得DMR。
A. 是
B. 否
C.
D.
【多选题】
ENESTfreedom 研究中,由于不稳定DMR没有尝试TFR资格的患者经达希纳治疗1年后可获得尝试TFR的资格。
A. 是
B. 否
C.
D.
【多选题】
ENESTnd标志性分析中,3个月时获得BCR-ABLIS≤10%与60个月时更佳的OS无关
A. 是
B. 否
C.
D.
【多选题】
ENESTnd标志性分析中,与伊马替尼相比,达希纳一线治疗更早获得分子学反应。
A. 是
B. 否
C.
D.
【多选题】
ENESTnd研究中,从第一年至第五年的随访中,达希纳和伊马替尼组累积的MR4.5相差的比例保持完全不变。
A. 是
B. 否
C.
D.
【多选题】
ENESTnd研究中,与伊马替尼相比,达希纳一线治疗组疾病进展至AP/BC显著更少。
A. 是
B. 否
C.
D.
【多选题】
ENESTnd研究中,在5年随访中,所有时间点达希纳组MMR的比例始终高于伊马替尼组。
A. 是
B. 否
C.
D.
【多选题】
ENESTnd研究中在伊马替尼治疗12个月内的MMR率为27%。
A. 是
B. 否
C.
D.
【多选题】
ENESTxtnd研究发现一线达希纳治疗反应欠佳或治疗失败后增加达希纳剂量可获得较高的MMR率。
A. 是
B. 否
C.
D.
【多选题】
IRIS研究随访10年, 32% 伊马替尼治疗患者由于不满意治疗反应中断治疗,>10%由于不良事件。
A. 是
B. 否
C.
D.
【多选题】
NCCN发表的关于TKI尝试停用之前需满足MR4 ≥ 3 年
A. 是
B. 否
C.
D.
【多选题】
NCCN指南中,CML-CP患者获得主要分子学反应的定义为定量PCR检测不到BCR-ABL转录本。
A. 是
B. 否
C.
D.
【多选题】
STIM格列卫停药研究。
A. 是
B. 否
C.
D.