【单选题】
Some old people don’t like pop songs because they cannot ___ so much noise.
A. resist
B. sustain
C. tolerate
D. undergo
查看试卷，进入试卷练习
微信扫一扫，开始刷题
答案
C
解析
暂无解析
相关试题
【单选题】
I have kept that portrait where I can see it every day, as it always ___ me of my university days in London.
A. recollects
B. reminds
C. recalls
D. invokes
【单选题】
The article suggests that when a person is under unusual ___ he should be especially careful to have a well-balanced diet.
A. weight
B. stress
C. press
D. nerve
【单选题】
You should hire a more ___ manager than the one you currently have.
A. sufficient
B. effective
C. respective
D. efficient
【单选题】
Surgeons began to ___ their hands and arms with soap and water before operating.
A. scrub
B. enhance
C. rub
D. exhibit
【单选题】
He might let something ___ in a moment of weakness.
A. slip
B. leak
C. to slip
D. to leak
【单选题】
The ___ for which he had fought all his life no longer seemed important to him.
A. aims
B. objectives
C. subjects
D. goals
【单选题】
Eating too much fat can ____heart disease and cause high blood pressure.
A. contribute to
B. attribute to
C. attest to
D. devote to
【单选题】
It soon ___ that what she loved was not my person but my wealth.
A. widened
B. expanded
C. extended
D. developed
【单选题】
I want to buy a new tie to ___ this brown suit.
A. go into
B. go after
C. go with
D. go through
【单选题】
Our company decided to ___ the contract because a number of the conditions in it had not been met.
A. destroy
B. resist
C. assume
D. cancel
【单选题】
I think it’s time I ___ in a new computer.
A. invested
B. insulted
C. interacted
D. impacted
【单选题】
The jeweler will ____ the inside of the ring with her name.
A. carve
B. engrave
C. cut
D. engross
【单选题】
They are _____ moving their office outside London.
A. considered
B. discussing
C. pondering
D. negotiating
【单选题】
Although she _____ the old pot thoroughly, she could not make it look completely clean.
A. scrubbed
B. washed
C. made
D. screwed
【单选题】
The mistake will remain an indelible ____ on his memory.
A. stain
B. thing
C. issue
D. accident
【单选题】
The wheel ____ through my frozen hand, and the car went right across the road.
A. slipped
B. sipped
C. dashed
D. disappeared
【单选题】
The cupboard was ____ with old fishing tackle.
A. stuffed
B. stocked
C. stored
D. filled
【单选题】
Teaching can be a tiring and ____ job.
A. meaningless
B. stressed
C. rewarded
D. stressful
【单选题】
The building is partly a museum and partly a private ____.
A. place
B. area
C. community
D. residence
【单选题】
They conferred on the best way to ______ business.
A. extend
B. adjust
C. expand
D. adopt
【单选题】
We had a party last month, and it was a lot of fun, so let’s have ____ one this month.
A. another
B. the other B. more D. other
【单选题】
I decided to go to the library as soon as I ____.
A. finish what I did
B. finished what I did
C. would finish what I was doing
D. finished what I was doing
【单选题】
The speaker, ______ for her splendid speeches, was warmly received by the audience.
A. having known
B. being known
C. knowing
D. known
【单选题】
No sooner had we reached the top of the hill ______ we all sat down to rest.
A. when
B. then
C. than
D. until
【单选题】
___ energy under the earth must be released in one form or another, for example, an earthquake.
A. Accumulated
B. Gathered
C. Assembled
D. Collected
【单选题】
Please ___ me for my rudeness. I really do not know the custom here.
A. engaged
B. comfort
C. execute
D. forgive
【单选题】
Sometimes it is very difficult to ___ some of the English words. Even the native speaker cannot help.
A. decrease
B. create
C. define
D. delight
【单选题】
In the wife’s eyes, his ___ to their marriage life is far from perfect.
A. requirement
B. commitment
C. participation
D. reflection
【单选题】
This newspaper often ___ the government’s opinion, not the public opinion.
A. affects
B. reacts
C. reflects
D. recognizes
【单选题】
It is predicted that heavy rains are ___ to flood the area in a few days.
A. frightening
B. threatening
C. scattering
D. warning
【单选题】
I chose to work abroad to improve my career ___.
A. future
B. path
C. prospect
D. expect
【单选题】
Long before I ever went there, Africa was alive in my ___.
A. image
B. imaginary
C. imaginative
D. imagination
推荐试题
【多选题】
2013年ELN指南推荐，伊马替尼治疗疗效欠佳的CML-CP患者可接受（ ）治疗。
A. 维持相同剂量伊马替尼治疗
B. 伊马替尼加量
C. 达沙替尼或尼洛替尼
D. 以上所有选项
【多选题】
2016中国CML指南中推荐分子学反应的监测频率为？
A. 每周进行一次，直至确认达到稳定MMR，随后每3个月进行一次
B. 每3个月进行一次，直到获得稳定MMR，随后应每3-6个月检测一次
C. 每3-6个月进行一次，直到获得稳定MMR，随后应每3-6个月检测一次
D. 以上所有选项
【多选题】
2017 ESMO定义的TKI治疗12个月提示治疗警告的指标为
A. "Ph+ 1%-65% ，BCR-ABL 1%-10% "
B. BCR-ABL 0.1%-1%
C. BCR-ABL < 0.1%
D. "Ph+ ≥ 1% ， BCR-ABL > 1%"
【多选题】
2017 ESMO定义的TKI治疗3个月达最佳反应标准为
A. "≥ PCyR (Ph+ ≤ 35%) ，BCR-ABL < 10% "
B. "Ph+ 36%-95% ，BCR-ABL > 10% "
C. "CCyR (Ph+ 0) ， BCR-ABL < 1% "
D. "Ph+ 1%-65% ，BCR-ABL 1%-10% "
【多选题】
2017 ESMO推荐CML治疗3个月BCR-ABLIS > 10% 达治疗警告时，应对患者
A. 筛查更密切，患者有可能的话换用其他药物治疗
B. 筛查更密切，每月一次
C. 换用其他TKI治疗，继续原TKI治疗或增加伊马替尼剂量为下一步 HCT进行评估
D. 以上都不对
【多选题】
CML预后分析Sokal积分公式中包含（ ）等预后因素。
A. 年龄、脾脏大小、血小板、原始细胞
B. 年龄、脾脏大小、血小板、嗜酸性细胞百分数
C. 年龄、脾脏大小、血小板、嗜碱性细胞百分数
D. 以上所有选项均错误
【多选题】
CML诊断标准包括（ ）。
A. 典型的临床表现
B. 有Ph染色体
C. 有BCR-ABL融合基因阳性
D. 典型的临床表现，有Ph染色体和/或有BCR-ABL融合基因阳性
【多选题】
DASISION研究的终点是（ ）。
A. 6个月内，证实获得的CCyR
B. 12个月内，证实获得的CCyR
C. 6个月内，证实获得的MMR
D. 12个月内，证实获得的MMR
【多选题】
ELN推荐，治疗12个月时的最佳疗效反应为（ ）。
A. BCR-ABL≤10%和/或CCyR（ 0%到35%，Ph+ 染色体）
B. BCR-ABLIS<1%和/或CCyR（0%，Ph+ 中期分裂）
C. BCR-ABL≤0.1%（MMR或更深）
D. BCR-ABL＞10%
【多选题】
ELN推荐，治疗3个月时的最佳疗效反应为（ ）。
A. BCR-ABLIS≤10%和/或PCyR（0%到35%，Ph+中期分裂）
B. BCR-ABLIS<1%和/或CCyR（0%，Ph+ 中期分裂）
C. BCR-ABL≤0.1%（MMR或更深）
D. BCR-ABL＞10%
【多选题】
ELN推荐，治疗6个月时的最佳疗效反应为（ ）。
A. BCR-ABL≤10%和/或PCyR（0%到35%，Ph+ 中期分裂）
B. BCR-ABLIS<1%和/或CCyR（0%，Ph+ 中期分裂）
C. BCR-ABL≤0.1%（MMR或更深）
D. BCR-ABL＞10%
【多选题】
ENESTchina的主要研究终点是（ ）。
A. 12个月的MMR，定义为BCR-ABL≤0.1%
B. 6个月的MMR，定义为BCR-ABL≤0.1%
C. 24个月的MMR，定义为BCR-ABL≤0.1%
D. 36个月的MMR，定义为BCR-ABL≤0.1%
【多选题】
ENESTnd 研究随访到5年时，达希纳300mgBID和伊马替尼组的患者中，达到MR4.5的患者的百分比是多少？
A. 32%、15%
B. 40%、 23%
C. 42%、 24%
D. 54%、 31%
【多选题】
ENESTnd 研究中，达希纳300mg BID 和伊马替尼组患者在12个月时累计的MMR率是多少？
A. 40% 和 23%
B. 54% 和 31%
C. 60% 和 31%
D. 55% 和 27%
【多选题】
ENESTnd 研究中，达希纳300mg BID 和伊马替尼组患者在三个月没有达到BCR-ABL ≤ 10%的百分比是多少？
A. 7% 和 29%
B. 7% 和 30%
C. 9% 和 30%
D. 9% 和 33%
【多选题】
ENESTnd 研究中，达希纳300mg BID 和伊马替尼组患者在以下哪个milstone的百分比分别为91%和 67%？
A. 6个月Bcr-Abl ≤ 1%
B. 6个月Bcr-Abl > 1%
C. 3个月Bcr-Abl ≤ 10%
D. 3个月Bcr-Abl > 10 %
【多选题】
ENESTnd 研究中，随访到第5年时，达希纳300mgBID和伊马替尼治疗组的患者中，累积达到MMR的患者的百分比是多少？
A. 55%、27%
B. 62%、40%
C. 76%、56%
D. 77%、60%
【多选题】
ENESTnd研究landmark分析中，达希纳300mg BID治疗第六年哪组患者的结局百分率为94.5%？
A. 3个月BCR-ABL > 10%的患者总生存期
B. 3个月BCR-ABL ≤ 10%的患者总生存期
C. 3个月BCR-ABL > 10%的患者无进展生存
D. 3个月BCR-ABL ≤ 10%的患者无进展生存
【多选题】
ENESTnd研究landmark分析中，达希纳300mg BID治疗第五年哪组患者的结局百分率为97%？
A. 3个月BCR-ABL > 10%的患者总生存期
B. 3个月BCR-ABL ≤ 10%的患者总生存期
C. 3个月BCR-ABL > 10%的患者无进展生存
D. 3个月BCR-ABL ≤ 10%的患者无进展生存
